A FATAL OUTCOME OF A NEONATAL DILATED CARDIOMYOPATHY: EVOLUTIVE NEONATAL LUPUS OR EARLIER CHILDHOOD- ONSET SYSTEMIC LUPUS? A CASE REPORT

Neonatal lupus is a rare congenital syndrome resulting from placental passage of maternal antibodies against SSA/Ro and/or SSB/La to the fetus. It generally benign condition, cardiac involvement determining prognosis. NNL rarely manifested by isolated cardiomyopathy. The subsequent evolution towards systemic and unpredictable. We report case daughter non-consanguineous marriage with healthy parents who presented dilated cardiomyopathy in first months her life complicated several outbreaks heart failure. spontaneous was marked occurrence skin lesions face arms at age 10 years, then installation episodes hydrous retention 12 years an acute renal insufficiency rapid fatal outcome 15 years. ANA rate threshold positivity, antiDNA ANCA were not detectable.C3 low. Although genetic cause can never be ruled out, diagnosis erythematous SLE (an eventual or childhood-onset lupus). propose decision tree for management neonatal NCMP as synthesis literature.The search anti SSA/SSB must part check-up usually requested time pregnancy. In addition, we strengthen knowledge medical profession, especially proximity health centers, on diseases better patients.